This neurodegeneration is accompanied by the formation of characteristic Lewy bodies, which are intracellular inclusions composed largely of aggregated and misfolded -synuclein ( This degeneration of dopaminergic neurons is strongly linked to the generation of reactive oxygen species and oxidative stress as well as mitochondrial dysfunction, neuroinflammation, and aging ( The interplay between mitochondrial function and GSH is especially critical in PD
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Exogenous taurine supplementation however, has shown some promising results on increasing time to fatigue during exhaustive exercise by up to 50% in rodents, and time to VO 2max in men [7981]
