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Acknowledgements This work was supported by grants from the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences (CIFMS, grant no

Fifty-four metabolites, associated with amino acid, organic acid, acylcarnitine and purine metabolism as well as microbiome-associated metabolites, were quantified using liquid chromatography-tandem mass spectrometry

Where they differ: GHK-Cu stimulation range: Published studies show GHK-Cu begins stimulating collagen synthesis at picomolar to low nanomolar concentrations (10-12 to 10-9 M), with effects documented on collagen types I, III, IV, and VII