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Large meta-analyses of over 100,000 participants have found no significant association between these medications and serious psychiatric events

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The patients who will do best on these medications over the long term are those who use them within a framework that protects lean mass, supports metabolic health, and addresses the behavioural and physiological underpinnings of weight regain

Ozempic is a specific brand of GLP-1 receptor agonist used to manage type 2 diabetes and obesity

) Specifically, the changes to the gut microbiome composition caused a reduction in the intestinal cells that produce mucin, which is the barrier that prevents microbes from causing inflammation in the gut

DOI 10.1016/j.xcrm.2025.102214.