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If a patient is deficient in active Vitamin B6 (a common occurrence due to the gut dysbiosis frequently seen in Long COVID), the transsulfuration pathway becomes completely blocked

Annu Rev Plant Biol 63:131152 Kocsy G, Tari I, Vankov R, Zechmann B, Gulys Z, Por P, Galiba G (2013) Redox control of plant growth and development

ACP6 is mitochondrial, supposed to participate in lipid metabolism through its characterized activity of hydrolyzing lysophosphatidic acid (135)

the elderly, strict vegetarians (i.e., vegan), and patients with malabsorption problems are more likely to become deficient