GLP-1 receptor agonists work by replicating the function of natural GLP-1, helping to restore these deficiencies
*Correspondence: Jens Juul Holst [email protected] This article was submitted to Molecular and Structural Endocrinology, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
The FDA has also said some companies are mass-marketing non-FDA-approved compounded GLP-1s as alternatives to approved drugs, and the agency is moving to restrict these practices as supply stabilizes
Especially on a low-calorie or low-protein diet, the body will break down some muscle tissue to provide nutrients to the brain and other organs
This extended exposure might increase the chance of side effects
Exercise improves insulin sensitivity, which tirzepatide also targets, and helps maintain the metabolically active lean mass that influences thyroid hormone requirements
