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The practical implication is that retatrutide users may need to be slightly less aggressive with food restriction to avoid an excessive caloric deficit that accelerates lean mass loss
That does not mean tirzepatide is weak
But the high up-front costs for name-brand drugs and the reliance on compounded medications (which arent FDA-approved) may give some users pause, especially if they prefer insurance-covered or in-person options
The dual-action formula worked even better
Retatrutide also delays gastric emptying, which may affect the timing of absorption of orally administered supplements, including NAD+ precursors
Like any other medicine, retatrutide can cause some side effects
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