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GLP-1 drugs are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

Yao H, Zhang W, Yang F, Ai F, Du D, Li Y

Obesity, a growing global health concern, is linked to genetic, environmental, and lifestyle factors that increase the risk of chronic diseases such as type 2 diabetes, cardiovascular disease, common cancers, and osteoarthritis, as well as significantly increasing healthcare costs during childhood and adolescence

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-Glutamylcyclotransferase knockdown inhibits growth of lung cancer cells through G0/G1 phase arrest

NF- B, nuclear factor- B