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According to the Saxenda SmPC, treatment is initiated at 0.6 mg daily and gradually increased over several weeks to the maintenance dose of 3.0 mg daily

What the Research Shows GLP-1 medications represent a meaningful advance, but they are not without limitations

Dose adjustments should be medically supervised to balance effectiveness, minimize gastrointestinal side effects, and ensure safe, sustainable long-term results

D.QuerciF.et al (2010b)

In patients with type 2 diabetes mellitus, RYBELSUS produced clinically significant reduction from baseline in HbA1c compared with placebo

This work was supported by the COST Action CA20114 PlasTher and the COST Action CA19110 PlAgri (supported by European Cooperation in Science and Technology) and internal grant from VETUNI Brno No