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Studies have further demonstrated improvements in metabolic measures such as reduced glycated hemoglobin or HbA1c, fasting plasma glucose levels, self monitored blood glucose profiles, and body weight, which suggests potential value for people looking to achieve better long term health outcomes

6-10 Tirzepatide also demonstrated reductions in lipids in each SURPASS trial: triglycerides decreased, HDL increased, and LDL decreased

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Agostinho FR, Rus GZ, Stringari RB, Ribeiro KF, Ferraro AK, Benedet J, Rochi N, Scaini G, Streck EL, Quevedo J (2011) Treatment with olanzapine, fluoxetine and olanzapine/fluoxetine alters citrate synthase activity in rat brain

From there, we repeat what works and shift what doesnt

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