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PMID: 21795304

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Another strategy involved the use of SIRT activator SRT1720 and the PARP inhibitor Olaparib, which enhanced SIRT1 activity and increased NAD + 111

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Vit-D is a negative regulator for expression of renin and interacts with the RAAS/ ACE/ACE-2 signaling axis, therefore could affect SARS-CoV-2 infection process as well as host CV/circulatory function 693