In the Phase 2 trial, participants on the 12 mg dose were still on a steep weight loss trajectory at 48 weeks, losing roughly 5-6 pounds per month even late in the treatment period
Yes, specific safety monitoring regarding the thyroid, pancreas, and kidneys is a standard part of the prescribing protocol
Nature 535 , 182186 (2016)
Effects of dapagliflozin on blood pressure in hypertensive diabetic patients on renin-angiotensin system blockade
Retrieved from Perkovic, V., Tuttle, K
The cardiovascular outcomes trial SUSTAIN-6, published in the New England Journal of Medicine, demonstrated cardiovascular safety in a population where many participants were receiving antiplatelet therapy