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Counteracting NSAID-Induced Damage One of the most compelling areas of BPC-157 research is its ability to counteract gastrointestinal damage induced by nonsteroidal anti-inflammatory drugs (NSAIDs)

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More specifically, the RGDL motif and stapled alpha-helix structure of peptide 5a mimic the binding interactions with the proTGF1/v6 complex, effectively preventing TGF from being activated (Nardelli et al., 2019)