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4a) or treatment with the pharmacological inhibitor BSO (Fig

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doi: 10.1016/j.molmet.2015.03.005 88 FebbraioMSilversteinRL

Peripheral peptide hormones are released postprandially and travel in the circulation to bind to their receptors in the homeostatic regulatory centers in the CNS, notably the arcuate nucleus (ARC) of the hypothalamus and the dorsal vagal complex (DVC) in the brainstem medulla