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ALA is a medium-chain fatty acid with a carboxylate on one end, which anchors onto proteins to perform as a co-enzyme

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Mello T, Zanieri F, Ceni E, Galli A

SURMOUNT-5 Trial A head to head trial between tirzepatide and semaglutide for the treatment of obesity SURMOUNT-5

Therefore, the low rate of patients reaching a complete proteinuria response in clinical trials might not necessarily indicate insufficient control of SLE activity but rather reflect a lacking appreciation and therapy of kidney damage accrual, and, more specifically, of CKD 12

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