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To improve the selectivity, in this work, we design and synthesize a malononitrile-functionalized TPE derivative, TPE-DCV, which can undergo addition reaction with thiol group to the alkene bond, leading to the change in its fluorescence in the system (Figure 1)

To study the interaction, 200 ng/l dsDNA incubated for 24 h at 37C, 100 rpm, in either absence or presence of 1 mM GSH at intrinsic pH or 1 mM GSH at neutral pH (7.2)

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Loreto, A., Di Stefano, M., Gering, M

Impact of medications on COVID-19 outcomes in inflammatory bowel disease: analysis of more than 6000 patients from an international registry