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PubMed Del Prato, S., Kahn, S.E., Pavo, I., Weerakkody, G.J., Yang, Z., Doupis, J., Aizenberg, D., Wynne, A.G., Riesmeyer, J.S., Heine, R.J., Wiese, R.J., & SURPASS-4 Investigators
Importantly, peptide effects often continue long after the compounds themselves are metabolized, making it essential for healthcare professionals to distinguish between biological activity and bloodstream presence
Nerve recovery studies run 6-12 weeks
The mechanistic data is strong
Koeth's 2013 work (PMID 23563705) showed that gut bacteria metabolize dietary carnitine into trimethylamine, which the liver converts to TMAO a metabolite that observational studies have associated with atherosclerosis and cardiovascular risk
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