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2007) as well as by Wang et al

Getting the dose right is critical because both under-dosing (reduced efficacy) and over-dosing (increased side effects) create problems that compound over time

Due to the continuous exposure to occlusal forces and periodontal microorganisms, alveolar bone possesses a unique immune microenvironment distinct from the long bones, with more frequent interactions between monocytes/macrophages and MSCs (Lin et al., 2021)

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Add EDC and DMAP (HOOC-SS-BBR:EDC:DMAP molar ratio = 1:1.5:1) to the anhydrous DMSO, followed by ASP