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Depletion of LARS B cell subsets by LARS gene ablation or Leu depletion can inhibit immune escape in CRC

Tirzepatide reduces 24-hour ambulatory blood pressure in adults with body mass index 27 kg/m 2 : SURMOUNT-1 Ambulatory Blood Pressure Monitoring Substudy

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This intervention reversed high intestinal permeability and levels of inflammatory cytokines (including TNF, IL-6, and IL-17), ultimately protecting against HFD-induced osteopenia