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Headaches Less common but reported by some users, particularly in the first two weeks

Some level of GLP-1 activation is infinitely better than none

Dropout was higher in the 12 mg arm than in the 9 mg arm, reinforcing a pattern already visible in Phase 2: the marginal efficacy gain from pushing to 12 mg comes at real tolerability cost

This is the single most important point for dose-selection decisions going forward and is the reason the 9 mg arm and the new 4 mg maintenance dose are under such close scrutiny

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One item was added to the initial 21, I feel that others perceive me as significant, as participants brought up this aspect when answering I feel significant to others