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Acetyl-L-carnitine suppresses apoptosis of thioredoxin 2-deficient DT40 cells

Peptide drugs, on the other hand, are manufactured to last longer in the body to create a therapeutic response, such as controlling appetite or promoting the growth of new blood vessels, bone density or muscle

On one hand, p53 reduces cystine uptake by inhibiting SLC7A11 expression, leading to impaired function of GPX4, thereby inducing ferroptosis in lesioned chondrocytes to eliminate damaged cells

[DOI] [PubMed] [PMC] Rivera JC, Espinoza-Derout J, Hasan KM, Molina-Mancio J, Martnez J, Lao CJ, et al

Representative research domains include: In vitro skin and connective tissue models examining fibroblast activity, ECM deposition, collagen organization, and responses to oxidative stress