Intracellular production of OH from H 2 O 2 is driven by the Fenton reaction, shown in Reaction 3 (43, 44, 48): As the most reactive known ROS, OH reacts with nearly all intracellular building blocks and macromolecules (amino acids, nucleic acids, phospholipids, sugars, proteins, RNA, DNA, lipids, polysaccharides)
The function of NQO1 is to catalyze the NADPH-dependent reduction of quinones to hydroquinones, thereby preventing the formation of highly reactive semiquinones and associated reactive oxygen species (ROS)
Enhanced glutathione production via fed-batch fermentation using the #14 mutant strain To assess the feasibility of industrial-scale glutathione production, fed-batch fermentation was performed in a 1 L bioreactor using the #14 mutant strain
The other amino acids are produced by the body and therefore do not have to come from our diet
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