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3D pixel colocalization analysis was performed using AIVIA software version 12 to quantify the percentage of MIM signals co-localized with CIP4 signals

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The protective effect of HO-1 in diabetic retinopathy is not only reflected in the inhibition of inflammation and oxidative stress but also promoted microglia polarization from the M1 state (pro-inflammatory) towards the M2 state (anti-inflammatory) [159]