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Twenty patients had hepatic resection for metastasized colorectal carcinoma (mCRC), 10 for hepatocellular carcinoma (HCC), 12 for intrahepatic or perihilar cholangiocarcinoma carcinoma (iCCA/pCCA), 1 for neuroendocrine liver metastasis (NELM), 1 for non-neuroendocrine non-colorectal (NNECR) liver metastasis and 2 patients had benign liver lesions

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Injection site reactions seem to be more commonly reported by people taking tirzepatide vs

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Retatrutide is not approved by Health Canada for any use

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Notably, GLP-1-producing neurons within the nucleus tractus solitarius (NTS) project axons to the VTA and other limbic structures, further embedding GLP-1 signaling within neural networks that regulate reward and motivation (Llewellyn-Smith et al., 2011

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Retatrutides success comes in large part from its potency against GLP-1 and its receptors

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Tirzepatide microdosing success does not predict retatrutide microdosing success because the glucagon receptor component changes the equation

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