glp 1 agonist delayed gastric emptying All patients on GLP1 agonists should be investigated with US if possible. Risk for gastric cannot be evaluated only in case of GI symptoms Gastrointestinal effects of GLP-1 receptor

Any safety discussion should therefore include downstream GH/IGF-1 effects as relevant endpoints

Its defining structural feature is the gamma-glutamyl linkage: the glutamate residue is joined through its side-chain carboxyl rather than the usual alpha-peptide bond, which makes the molecule resistant to most intracellular peptidases and means it is cleaved almost exclusively by gamma-glutamyl transpeptidase at the outer cell surface (Zhang, Forman and Choi, Methods in Enzymology, 2005)

Cystatin C is a newer blood marker of kidney function and has numerous advantages over standard tests

Radiculopathy occurs when a nerve root becomes compressed or irritated where it exits the spinal column

No evidence it causes cancer but could feed existing cancer

W., Craun, M