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Our findings highlight the potential of targeting glucose and glutamine pathways in GBM using dendrimer-based nanocarriers, overcoming the BBB and disrupting key metabolic processes in GBM cells

Animal acute toxicity studies across Sikiric's group publications have consistently shown a low acute toxicity profile, with no defined lethal dose identified in standard rodent models

Escalating the dose to chase a faster result is explicitly not the studied approach

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Pathohistological examinations of the spleen, heart, liver and lungs and hematological analyses were conducted

10.1016/j.eplepsyres.2019.03.009 Epilepsy Res