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Lixisenatide, another GLP-1 analogue, has also been reported to decrease atheroma plaque size and instability in animal models, by reprogramming macrophages towards M2 phenotype (10 g/kg/day) (30)

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NICE guidance supports the use of GLP-1 receptor agonists for type 2 diabetes (NG28) when certain criteria are met, typically after other treatments have been tried

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In clinical studies, Wang (41) et al

His knowledge of hormone physiology allowed him to recognize the peptides significance