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Because blood is pooling in the legs, less blood returns to the heart and brain, triggering dizziness, lightheadedness, and a compensatory spike in heart rate (tachycardia) as the heart desperately tries to pump the remaining blood upward

The ability of these medications to modulate appetite and energy expenditurepartly through delayed gastric emptying [25] and enhanced central satiety signaling [26]may account for these favorable outcomes

Western blot analysis Western blot analysis was performed with the same antibodies as the immunofluorescence assay in addition to Complex III (UQCRC2) and Complex V (ATPB)

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In the hyperacute stage, sudden hypoxia damages the BBB, leading to cytotoxic edema and increased permeability