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More reliable contraception options while on GLP-1s: IUDs (hormonal or copper) have excellent reliability on GLP-1s and are the most dependable option since theyre not affected by GLP-1s at all

Preclinical studies demonstrated that animals receiving Retatrutide lost more weight than calorie-matched controls receiving only GLP-1 agonists

Semaglutide isnt suitable for everyone

G.LiX.WuD.et al (2018)

This mechanism operates independently of weight loss, meaning the liver benefits may exceed what you would expect from the degree of weight reduction alone

Quick Answer: Using semaglutide after its expiration date is not recommended as the medication may have reduced potency, compromised sterility, and cannot be guaranteed safe or effective by the FDA or manufacturers