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2.1 Anti-inflammatory signaling and antioxidant effect Low-grade vascular inflammation is a central driver of atherogenesis, promoting monocyte recruitment, cytokine secretion, and plaque progression ( 2.2 Improvement of endothelial function and reduction of adhesion molecules Endothelial activation is an early biochemical event in atherosclerosis, characterized by increased expression of adhesion molecules, including Intercellular Adhesion Molecule 1 (ICAM-1), vascular Cell Adhesion Molecule 1 (VCAM-1), Monocyte Chemoattractant Protein-1 (MCP-1), and L-selectin

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The cost of medication is not included in the monthly membership fee and varies depending on if you pay cash or have insurance

75.4%) compared to the DPP-4i group, although these differences were below the minimum SMD threshold of 0.2

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Endocrinol Diabetes Metab (2020) 3(3):e00163