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doi: 10.1016/S0896-6273(01)00402-0

Due to the nature of a clonogenic assay, a measure of cellular proliferation, we investigated the effect of a 1 M APR-246 treatment on cell cycle dynamics

Nausea is the single most common side effect of GLP-1 receptor agonist medications and the most common reason patients in clinical trials and in clinic discontinue treatment

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TGR5 activation leads to downstream GLP-1 secretion [107], ameliorating glucose regulation and glycogen synthesis in animal models with diabetes