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IGSRT is especially effective for basal and squamous cell skin cancers on the leg, and it is often preferred on cosmetically sensitive areas such as the knee cap or inner thigh where scarring may be more noticeable

1982 ( Clinical Orthopaedics and Related Research 171:264-272, PMID 7140077), direct electric currents ranging from 10 microA to 1000 microA increased ATP concentrations in rat skin tissue, with peak ATP production reported at 500 microamps and decline above that threshold per secondary literature analysis