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Telomere shortening can be counteracted by telomerase which, in highly regulated ways, adds telomeric repeats to the ends of chromosomes 27

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It does so by activating endogenous antioxidant systems and restoring mitochondrial integrity, which are both cornerstones of healthy aging

doi: 10.3389/fnmol.2024.1441575 10 BirbenESahinerUMSackesenCErzurumSKalayciO

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those above 1000 Da absorb poorly without penetration enhancers such as cyclodextrins or bile salts