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For longer-term storage, freezing at approximately 20 C is recommended to maintain structural integrity and limit degradation

It is important to note that many of the studies that examined the efficacy of lipoic acid in the treatment of diabetic neuropathy have been primarily conducted by one German research group and funded by the manufacturer of lipoic acid in Germany (82)

Applied Food Biotechnology, 8(1), 5769

Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2

Another mechanism involves bile acids , which are released during fat digestion

In laboratory environments, Lipo-C formulations are primarily investigated for their influence on fat metabolism, methylation processes, and nutrient-driven energy pathways