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Together, the figure highlights the mechanisms and functional advantages of each platform for cancer-targeted therapies

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To date, nearly 50 clinical trials have been conducted on the anticancer effect of melatonin in cancer therapy, all demonstrating significant and promising results

Disruption of ciliary function by pyocyanin (see Section 2.1.1) further deteriorates mucociliary clearance of thickened mucus, leading to microbial-mediated acute exacerbation often seen in CF and COPD (177, 178)