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Lost 47 pounds in 10 months and it's stayed off
Secondly, GLP-1 receptor agonists carry important safety considerations including risk of pancreatitis, gallbladder disease, and potential thyroid C-cell tumours (based on rodent studies, though human relevance remains uncertain)
They used flow cytometry to investigate the effect of GLP-1/GLP-1R on the polarization of macrophages
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There are no legitimate long-term data to support it
While these adverse effects do not typically outweigh the substantial metabolic benefits, they may limit use in specific patient populations, necessitating careful dose titration and clinical monitoring
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