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CLA: Take with your largest meals to ensure proper absorption and digestive comfort

In the 72-week study of more than 1,600 overweight or obese adults with Type 2 diabetes, those who received the 36-milligram highest dose of orforglipron on average shed 10.5% of their weight, or about 23 pounds, versus 2.2% for those who received a placebo, achieving the main goal of the trial

Dose Titration Table | Week | Tirzepatide Dose | |------|-----------------| | 1 to 4 | 2.5 mg weekly | | 5 to 8 | 5.0 mg weekly | | 9 to 12 | 7.5 mg weekly | | 13 to 16 | 10.0 mg weekly | | 17 to 20 | 12.5 mg weekly | | 21+ | 15.0 mg weekly (max) | Patients who cannot tolerate a dose increase may stay at the current dose for an additional 4 weeks before attempting the next step

You also need to tell your doctor about all the other medicines you are taking, especially those used to treat high blood pressure or heart conditions

Wegovy is contraindicated with a personal/family history of medullary thyroid carcinoma (MTC) or MEN 2

LAE102 has received IND approvals in both China and the United States for the treatment of obesity, and Phase I clinical trials are progressing rapidly in both countries