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Without the appetite-suppressing effect of elevated norepinephrine, hunger returns to pre-treatment levels, and weight creeps back up

GLP-1 is a naturally produced hormone in the gut in response to food

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Effect of oral semaglutide on energy intake, appetite, control of eating and gastric emptying in adults living with obesity: A randomized controlled trial

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Research shows consuming 1.0-1.6g per kg body weight helps preserve muscle mass during rapid weight loss