Over time, this leads to consistently higher drug levels, more side effects, and a pattern that can mimic overdosing
Two developments stand out as particularly important for Canadian patients
Refund boundary: What changes once a visit happens, a prescription is sent, medication ships, or a lab kit is used
The treatment of type 2 diabetes in the presence of renal impairment: what we should know about newer therapies
The mechanism(s) by which GLP-1RAs would cause NAION is also unclear, particularly as GLP-1RAs are associated with neuroprotective properties and reductions in ischemic risk (96), but it has been hypothesized to be related, like the exacerbation of retinopathy, to rapid improvements in glycemic control (Figure 3)
Long-term safety, tolerability, and weight loss associated with metformin in the Diabetes Prevention Program Outcomes Study