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Postmenopausal women who lose a significant amount of weight may also need to pay extra attention to bone health to guard against osteopenia or osteoporosis, he adds

studies provide compelling evidence that semaglutide use in orthopedic surgery is associated with lower rates of infection, readmission, and revision surgery, likely due to improved metabolic control, reductions in systemic inflammation, and weight loss-driven perioperative risk reduction

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The first study (2023) evaluated 7,051 patients undergoing TKA who were prescribed semaglutide preoperatively, comparing them to a matched control group of 34,524 non-users