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Bergoni Institute, Bordeaux
Cytokines and chemokines secreted by leukocytes, such as tumor necrosis factor, IL-6, and granulocyte colony-stimulating factors to name a few activate endothelial cells, stimulate neovascularization and leukocyte migration, and cause expansion of synovial fibroblast-like and macrophage-like cells [68]
Clinical insight: Most people reading this arent truly choosing between medicationstheyre trying to fix stalled fat loss, insulin resistance, or visceral fat that hasnt responded to diet, exercise, or even GLP-1 therapy alone
Regarding immune protection, early microbial colonization is pivotal for immune system maturation