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It is classified as a triple incretin receptor agonist, targeting the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors simultaneously

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Triple receptor engagement raises complex questions about signaling balance, receptor selectivity, tissue-specific effects, cellular communication, and downstream gene expression pathways

doi: 10.1016/j.bcp.2024.116192 77 YamazakiTTakahashiCTaniguchiYNarukawaMMisakaTAnoY

The first line segment dominated the GLP-1 targeted peptide weight loss drugs market in 2024 and is expected to continue its growth trajectory in the upcoming period, as these drugs are increasingly being prescribed early in the treatment of obesity and related metabolic conditions