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Mitophagy-mediated self-elimination is essential for tissue regeneration The present study demonstrated that mitophagy is sufficient and required for hair regeneration

[12] [13] Established therapies remain the standard of care: topical treatments (corticosteroids, vitamin D analogues), phototherapy, conventional systemic agents (methotrexate, ciclosporin), and biological therapies targeting specific immune pathways (TNF- inhibitors, IL-17 inhibitors, IL-23 inhibitors)

Therefore, targeting GPX4 transcription and neutrophil ferroptosis may have therapeutic benefits for SLE patients

Preventing Long-Term Issues: Ongoing swelling can cause serious health problems, like autoimmune diseases and cancer

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These sites are cleaved by the AP endonuclease, APE1, and corresponding nucleotides are then located into the gap by a DNA polymerase through two different sub-pathways, to finally be ligated by a DNA ligase (Krokan and Bjoras, 2013)