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GLP-1R, widely distributed in the central nervous system, plays a crucial role in regulating various brain pathological processes, including neuroinflammation, nutrient metabolism, mitochondrial function, and synaptic function [50,51,52]

Severe ovarian pathological diseases, such as polycystic ovary syndrome and premature ovarian insufficiency (POI), are caused by anomalies in folliculogenesis 2,3