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However, GPR40 but not GPR120 knockout mice exhibit impaired GLP-1 secretion from dietary fat, and only GPR40 agonists induce GLP-1 release in vitro and in vivo 106,110,111,112

Glossary of Key Terms GLP-1 (Glucagon-Like Peptide-1) A hormone produced in the intestines that slows gastric emptying, increases insulin secretion, and reduces appetite

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At the time of this writing, the data is sparse on the impact of these medications on the gut microbiota

Any use carries significant risks including potential serious adverse effects