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Both SSTR2 and SSTR5 mediate the antiproliferative effects of SS by tyrosine phosphatase activation and ERK1/2 phosphorylation inhibition, respectively, whereas only SSTR2 and SST3 subtypes mediate apoptotic effects (912)

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The brokerage estimates Indias weight-loss market at about $500 million, which could rise to $1 billion with the right pricing, adoption and government incentives. Generic drugmakers are also experimenting with a range of delivery formats, including single-use pre-filled syringes, single-shot pen injectors, vials, and reusable pens with adjustable dosing, the people familiar with the matter said

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