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Description

SUMO2 and SUMO3 interacted and modified several AR-associated coregulators (p300, SRC2, BAF proteins) and pioneering factors (FOXA1, HOXB13) associated with ARE-bound AR, demonstrating that SUMOylation amplified interactions with its transcriptional complex

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Exhibit minimal impact on cortisol and prolactin pathways in controlled studies

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