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Additionally, -blockers exert their effects primarily through the blockade of -adrenergic receptors, leading to a cascade of intracellular signaling events that ultimately influence gene expression mediated by transcription factors like MEF2 (myocyte enhancer factor 2), which is a crucial regulator of genes involved in cardiac hypertrophy and myocyte survival

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It helps regenerate other antioxidants like Vitamin C and glutathione, extending their lifespan in the body

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PMID 11695986