Published 2018 Jul 7
One serious AE of diverticulitis occurred in the anti-GDF8 6 mg/kg + anti-ActA 10 mg/kg Q2W 3 group after week 28 in a subject with a prior history of diverticulosis and was considered not related to treatment by the investigator
Uetake R, Sakurai T, Kamiyoshi A et al (2014) Adrenomedullin-RAMP2 system suppresses ER stress-induced tubule cell death and is involved in kidney protection
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On the last 3 d of TAM/vehicle injection, mice also all received daily bromodeoxyuridine (BrdU) injections (150 mg/kg/d, i.p.)
In addition, advanced glycocalyx fixation techniques (such as HPF and FS), along with visualization methods like TEM, reveal variations in glycocalyx thickness across vascular beds, providing new insights into its structural heterogeneity [35]