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The positive correlation between GST gene polymorphisms and hepatocellular carcinoma caused by hepatitis B virus chronic infection [55] and uterine cancer associated to human papilloma virus infection was described [56] (Figure 3)

IGF-1 and GH both play a role in collagen production, which directly affects skin tone, elasticity and hydration

Similarly, exposure to methylglyoxal, a reactive dicarbonyl compound formed as a metabolic byproduct of glycolysis, has been shown to inhibit glycolysis, leading to a reduction in ATP and GSH concentrations

Case example : A patient receives percutaneous and intradermal allergy tests (see Allergy section)

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however, due to the detoxification reaction, some patients may experience mild headaches or nausea.