glp-1 and glp-2 Targeting GLP-1, GIP & GCG in Obesity Type 2 Diabetes Research Frontiers | GLP-1 and GLP-2

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The Cu(II)/Cu(I) redox couple generates reactive oxygen species through the Fenton-like pathway: Cu(II) + O Cu(I) + O Cu(I) + HO Cu(II) + OH + OH Hydroxyl radicals (OH) are highly reactive and immediately oxidize susceptible amino acids

[1] [2] The synergistic effect of dual receptor activation appears to produce substantial weight loss and appetite reduction, though the complete mechanism of action is not fully characterized

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The only protection is realized via the strict control of iron metabolism (49)

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